The permissions of a mobile app are one of the most fundamental components for protecting the user's privacy and security. Unfortunately, developers frequently misuse permissions by requiring too many or too few permissions, or by not adhering to permission best practices. These permission-related issues can negatively impact users in a variety of ways, ranging from a poor user experience to severe privacy and security implications. To better understand permission-related issues during the app's development process, we conducted an empirical study of 2,002 GitHub repositories of open-source Android apps. We analyzed the occurrences of four types of permission-related issues across the lifetime of the apps.